Cushing's Disease or Cushing's Syndrome



Fund Type


Maximum Award Level


Pharmacy Card Fund


Minimum Copay
Reimbursement Amount

Minimum Copay Reimbursement Amount

We encourage you to please use your HealthWell pharmacy card for any applicable charges as possible.


Minimum Premium
Reimbursement Amount

Minimum Premium Reimbursement Amount

We encourage you to please submit monthly reimbursement claims (even if your premium is paid on a bi-weekly basis).


Household Income Limit

500% of the Federal Poverty Level
(adjusted for household size and high
cost of living areas)

Fund Alerts

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Treatments Covered

  • Acthrel
  • Cyproheptadine
  • Isturisa
  • Ketoconazole (oral Formulations Only)
  • Korlym
  • Lysodren
  • Metopirone
  • Recorlev
  • Signifor
  • Signifor Lar

Fund Definition

Co-payment or premium assistance for eligible beneficiaries to obtain prescription drug (or biologic) treatment for Cushing's Disease or Cushing's Syndrome.

Grant Utilization

HealthWell estimates that patients use an average of $9,830 during their 12-month grant period for this disease area.

Consider Premium Assistance

Under this fund, HealthWell can assist with premium costs. Medicare supplemental policies can help with cost shares related to many aspects of your health care. Using a HealthWell grant to cover premiums may be a better option than treatment-specific cost shares.

Do I Qualify?

HealthWell bases eligibility on an individual’s medical, financial and insurance situation. To qualify for HealthWell’s assistance, applicants must meet the following eligibility requirements:

  • Please make sure that HealthWell currently has a fund for your diagnosis/indication and that your medication is covered under that fund by visiting our Diseases and Medications listing. If we do not have a fund that currently covers your diagnosis, please check back as we frequently open and reopen programs as funding becomes available. The Foundation is able to help patients receiving treatment for indications for which we currently have an open fund. We can only assist with medications that have been prescribed to treat the disease/covered diagnosis. You will be asked to provide the Foundation with the patient’s diagnosis, which must be verified by a physician, nurse practitioner, or physician assistant’s signature. The patient must receive treatment in the United States.

  • To qualify for assistance from HealthWell, you must have some form of health insurance (private insurance, Medicare, Medicaid, TriCare, etc.) that covers part of the cost of your treatment. The Foundation will refer patients without prescription insurance to other programs, such as manufacturer patient assistance programs.

  • HealthWell assists individuals with incomes up to 300-500% of the Federal Poverty Level. The Foundation also considers the number in a household and cost of living in a particular city or state. If you believe you qualify for assistance, you may begin the application process here.
  • If you are receiving treatment in the U.S. and have met the eligibility criteria as listed, you are ready to apply! Please note that you will be asked to provide a Social Security Number in order to create a grant. This information is gathered to eliminate duplicate applications and is kept secure and confidential.

About Cushing’s Disease or Cushing’s Syndrome

Cushing’s Disease (a form of Cushing’s Syndrome) is caused by elevated levels of the hormone, cortisol, which helps maintain blood sugar levels, stops (suppresses) inflammation, and protects the body from stress. Cortisol is produced by the adrenal glands and is triggered by the release of adrenocorticotropic hormone (ACHT) from the pituitary gland. Cushing’s disease occurs when a non-cancerous tumor forms in the pituitary gland, causing excessive release of ACHT and elevated production of cortisol.

According to the National Institutes of Health, it is estimated that Cushing’s Disease occurs in 10 to 15 people per million worldwide and affects females more often than males. The condition usually occurs in adults between the ages of 20 and 50, but children may also be affected. Source: National Institutes of Health

Cushing’s Syndrome is a disorder with physical and mental changes that result from too much cortisol in the blood for a long period of time. Cushing’s Syndrome can be caused by factors outside the body (exogenous), due to cortisol-like medications such as prednisone, or factors within the body (endogenous), most often caused by hormone-secreting (usually non-cancerous) tumors of the adrenal or pituitary glands. Treatment for Cushing’s Syndrome depends on the cause and can include stopping cortisol-like medications or surgery to remove the tumor that is causing the high cortisol levels. Source: Endocrine Society

Additional Educational Resources

You may also visit our Resource List to view other copayment organizations that may provide assistance.