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Homocystinuria and Organic Acidemias

Treatments Covered

  • Ammonul
  • Arginine (non Otc)
  • Betaine
  • Biotin (non Otc)
  • Buphenyl
  • Carbaglu
  • Carglumic Acid 
  • Carnitor
  • Citrulline (non Otc)
  • Citrulline Easy
  • Cyanocobalamin (b12) (non Otc)
  • Cyanokit (non Otc)
  • Cystadane (non Otc)
  • Dextrose (non Otc)
  • Fabb (non Otc)
  • Flagyl 375
  • Folbee (non Otc)
  • Folbic (non Otc)
  • Folic Acid (b6 And B12) (non Otc)
  • Foltx (non Otc)
  • Glycine (non Otc)
  • Hydroxocobalamin (b12)
  • L-citrulline
  • Levocarnitine (non Otc)
  • Metrocream
  • Metrogel
  • Metronidazole Avpak
  • Metronidazole Novaplus 
  • Metronidazole 
  • Noritate
  • Nuvessa
  • Pyridoxine (b6) (non-otc)
  • Rifaximin
  • Rosadan
  • Rosadan Gel
  • Sodium Benzoate
  • Sodium Benzoate/sodium Phenylacetate
  • Sodium Phenylacetate
  • Sodium Phenylbutarate
  • Vandazole
  • Xifaxan

Fund Definition

Assistance with the prescription drugs and biologics used in the treatment of homocystinuria and organic acidemias.

Grant Utilization

HealthWell estimates that patients use an average of $2,850 during their 12-month grant period for this disease area.

Consider Premium Assistance

Under this fund, HealthWell can assist with premium costs. Medicare supplemental policies can help with cost shares related to many aspects of your health care. Using a HealthWell grant to cover premiums may be a better option than treatment-specific cost shares.

Do I Qualify?

HealthWell bases eligibility on an individual’s medical, financial and insurance situation. To qualify for HealthWell’s assistance, applicants must meet the following eligibility requirements:

  • Please make sure that HealthWell currently has a fund for your diagnosis/indication and that your medication is covered under that fund by visiting our Disease Funds listing. If we do not have a fund that currently covers your diagnosis, please check back as we frequently open and reopen programs as funding becomes available. The Foundation is able to help patients receiving treatment for indications for which we currently have an open fund. We can only assist with medications that have been prescribed to treat the disease/covered diagnosis. You will be asked to provide the Foundation with the patient’s diagnosis, which must be verified by a physician, nurse practitioner, or physician assistant’s signature. The patient must receive treatment in the United States.

  • To qualify for assistance from HealthWell, you must have some form of health insurance (private insurance, Medicare, Medicaid, TriCare, etc.) that covers part of the cost of your treatment. The Foundation will refer patients without prescription insurance to other programs, such as manufacturer patient assistance programs.

  • HealthWell assists individuals with incomes up to 300-500% of the Federal Poverty Level. The Foundation also considers the number in a household and cost of living in a particular city or state. If you believe you qualify for assistance, you may begin the application process here.
  • If you are receiving treatment in the U.S. and have met the eligibility criteria as listed, you are ready to apply! Please note that you will be asked to provide a Social Security Number in order to create a grant. This information is gathered to eliminate duplicate applications and is kept secure and confidential.

About Homocystinuria

Homocystinuria is elevation of the amino acid, homocysteine (a protein building block), in the urine or blood. Acquired forms of elevated homocysteine are usually due to lack of vitamins B6 (pyridoxine), B9 (folate), or B12 in one’s diet or the inability of the stomach to absorb the vitamins. Source: HCU Network America

About Organic Acidemias

Organic acidemias are a group of inheritable genetic metabolic disorders in which there is a defect in protein metabolism where an essential enzyme is absent or malfunctioning. This defect results in a buildup of chemicals, in this case usually acids, on one side of the metabolic blockage and a deficiency of vital chemicals on the other. This causes an overdosage of one chemical (often toxic) and the shortage of another which is essential to normal body functioning.

The effect of the disorder will depend upon the age at which symptoms occur. Children with less severe forms of the conditions develop symptoms later. Characteristics of the conditions include general malaise, reluctance to feed, breathing problems, vomiting, hypotonia (floppiness) and/or spasticity (stiffness). Early detection and treatment can greatly mitigate the effects of the disorder. Source: Organic Acidemia Association

Additional Resources

You may also visit our Resource List to view other copayment organizations that may provide assistance.

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